Our research applies computational microbiology approaches to investigate the evolution, spread and resistance of high-priority bacterial pathogens. We focus on global enteric and hospital-associated pathogens, including Shigella and Klebsiella species.

We investigate the mechanisms of antimicrobial resistance, including mapping how mobile elements and plasmids drive the spread of resistance genes between and across species. Central to our lab’s mission is translation of our science, bridging the gap between discovery science and public health or hospital settings.

Currently, our lab is the bioinformatics lead for the international ESGEM-AMR consortium, which is estabilishing a standard framework for the interpretation of genotypic antimicrobial resistance.